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Red cloverTrifolium pratenseThis familiar plant is native to Europe, northern Africa, and central Asia, but red clover is also grown for pasturage and as a rotation crop in the Americas and Australia. (Nodules on the roots fix nitrogen, enhancing the soil.) American children traditionally love hunting in a patch of red clover for a rare four-leaf specimen said to cause good luck, but it is the dried flowers that are used in herbal medicine. Red clover blossoms are believed useful as an expectorant and for the treatment of bronchitis and asthma. Red clover has also been used topically to speed wound healing and treat psoriasis. Current interest in red clover focuses on its use to relieve menopausal symptoms. Cattle and sheep grazing too heavily on clover have fertility problems because of their phytoestrogen intake. Red clover contains approximately 0.17 percent phytoestrogens. These include formononetin, genistein ,daidzein, and biochanin A. A volatile oil in the blossoms contains methyl salicylate, among other constituents. Some coumarin derivatives and cyanogenic glycosides have also been isolated. The use of red clover extract as a supplement for menopausal women has gained
attention through the marketing of an Australian product called Promensil. These
pills, introduced in the United States in 1998, contain 40 mg each of isoflavones, in a standardized ratio.
Most of the research supporting
red clover isoflavones has been conducted in Australia. The same firm
markets a red clover supplement
called Trinivin, also containing 40
mg standardized isoflavones, for
men with healthy but enlarged
prostates. The characteristic red blossoms of this extensively cultivated forage plant have been subjected to detailed chemical analyses. More than one-third of a page of fine print in a recent reference is required just to list the names of the chemical compounds detected in red clover. Yet none of these various pigments, phenolic compounds, tannins, and the like has any pronounced therapeutic value, particularly in the treatment of venereal disease. The statement that red clover tea sweetened with honey and drunk two or three times a day for a period of four to six weeks will purify the blood (euphemism for cure venereal disease) is simply not factual. It is true that the obvious symptoms of the disease may disappear in that time, but no cure has been obtained. Four isoflavones found in red clover blossoms, formononetin, biochanin A, daidzein and genistein, do have mild estrogenic activity. This perceived effect has resulted in the introduction of a widely advertised red clover blossom dietary supplement product from Australia as a "natural choice for maintaining estrogen." Clinical studies to support these claims are apparently under way. The isoflavones found in red clover, and more common food sources such as soy beans, may alter hormone production or metabolism, intracellular enzymes, cell differentiation and production, and growth factors. Epidemiological studies suggest potential value of isoflavones in chemoprevention (cancer prevention), in Asian countries where soy products, rich in isoflavones, are widely consumed. A recent in vitro study found that biochanin A from red clover inhibited carcinogen activation in cell cultures, suggesting the need for further studies. Other names
Parts usedFlower heads. UsesRed clover is used to treat skin conditions, normally in combination with other purifying herbs such as burdock (Arctium lappa) and yellow dock (Rumex crispus). Red clover is also expectorant and may be used for spasmodic coughs. Red clover's estrogenic effect may be of use in treating menopausal complaints. Habitat & cultivationNative to Europe and Asia, and naturalized in North America and Australia, red clover is widely cultivated for hay and as a nitrogen-fixing crop. The flower heads are collected when newly opened in summer. ResearchThere has been little research into red clover's medicinal actions, but it is known that the red clover has a contraceptive effect in sheep. ConstituentsRed clover contains phenolic glycosides, flavonoids, salicylates, coumarins, cyanogenic glycosides, mineral acids. How much to takeUsually, red clover is taken as a tea by adding 250 ml (1 cup) of boiling water to 2 - 3 teaspoons of dried flowers and steeping, covered, for ten to fifteen minutes. Three cups can be drunk each day. Red clover can also be used in capsule or tablet form in the amount of 2-4 grams of the dried flowers or 2-4 ml of tincture three times per day. Dried red clover tops are also available in capsules, tablets, and tinctures. Side effectsNo fermented red clover is relatively safe. However, fermented red clover should be avoided altogether. Applications
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